Retain this medication inside the carton or container it came in, tightly closed, and away from arrive at of kids. Retail store promethazine tablets and liquid at room temperature and clear of excessive warmth and moisture (not in the toilet). Retailer promethazine suppositories while in the fridge. Protect the medication from light-weight.
Postmarketing cases of respiratory depression, which includes fatalities, are claimed with use of promethazine in pediatric people. Concomitant administration with other respiratory depressants may perhaps increase the possibility of respiratory melancholy.
Usually do not flush medications down the toilet or pour them right into a drain Until instructed to take action. Correctly discard this product or service when it's expired or no longer necessary. Speak to your pharmacist or neighborhood squander disposal organization.
A residence teaspoon is just not an correct measuring device and could lead to overdosage. For prescriptions the place a measuring system will not be presented, a pharmacist can provide an acceptable measuring product and can provide Directions for measuring the proper dose. Do not overfill. Rinse the measuring unit with drinking water right after Each and every use.
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Bit by bit cutting down the dosage under the supervision of a health care provider is the most secure way to prevent employing opioids. Opioid withdrawal may be lifestyle threatening for a lot of people.
Box Warning: Pediatric patients with being overweight or disorders that can impair respiration, including those using a history of tonsillectomy or adenoidectomy.[22]
The following adverse reactions happen to be discovered in the course of scientific reports, from the literature, or in the course of write-up-approval use of codeine and/or promethazine.
Employing this drugs with any of the following medicines is just not encouraged. Your medical professional may possibly make a decision not to deal with you with this particular medication or adjust a lot of the other medicines you're taking.
Making use of this medicine while you are Expecting may possibly cause serious undesirable effects, like neonatal withdrawal syndrome with your newborn child. Notify your physician at once if you think that you happen to be pregnant or if you intend to be Expecting though employing this drugs.
Codeine triggers a reduction in motility linked to a rise in easy muscle tone while in the antrum with the tummy and duodenum. Digestion of food stuff inside the smaller intestine is delayed Promethazine codeine syrup and propulsive contractions are lowered.
Opioids are demonstrated to get many different effects on components on the immune program in in vitro and animal products. The clinical significance of these findings is unfamiliar. All round, the results of opioids look like modestly immunosuppressive.
Cough: Codeine is beneficial in managing several etiologies developing Continual cough. Continual cough can derive from many pathological states, with codeine getting variably efficient at treating the cough depending on the underlying etiology.
Hepatic impairment: According to producer labeling, no studies are already done on individuals with hepatic impairment. Consequently clinicians ought to prescribe codeine in a lessen dose in these sufferers.